Iifilimu zomlomo
Iifilimu zokuchithwa komlomo (i-ODF) yimo yemozulu eqinileyo yokukhupha kwangoko eyokukhutshelwa ekwakhiwe ngokubanzi isetyenziswe phesheya kwiminyaka yakutshanje. Yavela ngasekupheleni kweminyaka yoo-1970. Emva kophuhliso, ivele ngokuthe ngcembe kwimveliso yokhathalelo lwempilo elula. Uphuhliso luye lwanda kwicandelo leemveliso zokhathalelo lwempilo, iimveliso zononophelo lobuqu, kwaye utsalele umdla omkhulu kwaye uthuthane ngenxa yeengenelo zokuba ezinye iifomu zedosi azinazo. Iba yinto ebaluleke kakhulu yokuhambisa iziyobisi, ngakumbi ekulungeni izigulana ezinzima kunye neziyobisi ngendlela eqatywe kakhulu.
Ngenxa yomthamo owodwa oxhaphakileyo yokufumana iifilimu zokuchithwa ngomlomo, inamathemba asebenza kakuhle. Njengendlela entsha yedosi entsha enokuthi ithathe indawo yetafile yomlomo, iinkampani ezininzi ezinkulu zinomdla kule, ukwandisa ixesha lelungelo elilodwa lomenzi weziyobisi nge-dosage ye-dosage sisihloko sophando esikhoyo.
Iimpawu kunye nezibonelelo zokusetyenziswa komlomo
Akukho sidingo sokusela amanzi, kulula ukuyisebenzisa. Ngokubanzi, imveliso yenzelwe ukuba ibe yisayizi yesitampu, enokuchithwa ngokukhawuleza elulwimini kwaye iginye ngentshukumo eqhelekileyo yokuginya; ulawulo olukhawulezileyo kunye nokuqalisa ngokukhawuleza; xa kuthelekiswa nendlela ye-mucosal ye-mucosal, indlela yomlomo inokwenzeka ukuba ibangele ukonakala kwe-mucosal, kunye nomsebenzi wayo owomeleleyo; I-cavity ye-mucosal yolawulo inokuhlengahlengiswa ekuhlaleni ngokwemilinganiselo yezicubu yokuqhubela phambili ukususwa kwexesha likaxakeka; Ichiza lisasazwa ngokulinganayo kwizinto zokwenza ifilimu, umxholo uchazekile, kwaye uzinzo namandla zilungile. Ifaneleke ngakumbi amalungiselelo abantwana okwangoku abonelela ngokufutshane eTshayina. Inokucombulula ngokulula iingxaki zabantwana nezigulana kwaye iphucule ukuthotyelwa kwabantwana kunye nabaguli abalupheleyo. Ke ngoko, iinkampani ezininzi zamachiza zidibanisa amalungiselelo ayo afumanekayo, iicapbules, iitafile kunye nefilimu yomlomo itheyibhile iguqulwe kwifilimu yomlomo yokwandisa ngokukhawuleza ukwandisa umjikelo wobomi bemveliso.
Izinto ezingalunganga zefilimu yomlomo
I-oral cavity inokufunxa i-MUCOSA ngendawo encinci. Ngokubanzi, i-membrane yomlomo incinci kwivolumu kunye nokulayisha ichiza akulunganga (ngesiqhelo i-30-60mg). Kuphela ziziyobisi ezisebenzayo zinokukhethwa; Ichiza eliphambili lifuna ukuba nemaski-yemaski, kwaye isikhumba sengcambu yechiza ichaphazela ukuthobela indlela; Ukuzibandakanya kwamathe amangaphuli kunye nokuginya kuchaphazela ukusebenza kwempumelelo ye-MUCOSA ye-Oral Mucosa; Ayizizo zonke izinto ezinokudlula kwi-MUCOSA yomlomo, kwaye ukuthathwa kwazo kuyachaphazeleka ngokufa kwamafutha; Isidanga sokudodobala, ubunzima bemoyari, njl.; kufuneka isetyenziswe phantsi kweMeko ethile ye-Angerquator; Ngexesha lokwenza ifilimu, umbandela ushushu okanye i-Solvent ivela, kulula ukugwetywa, kwaye kulula ukuwa ngexesha lokucheba, kwaye kulula ukwaphuka ngexesha lokusika; Ifilimu incinci, ukukhanya, incinci, kwaye kulula ukuyifumana ukufuma. Ke ngoko, iimfuno zokupakisha ziphezulu, ezingafanelekanga zilungele ukusetyenziswa, kodwa zikwaqinisekisa umgangatho wamayeza.
Ukulungiswa kwefilimu yefilimu ethengiswa phesheya
Ngokweenkcukacha-manani, imeko yefomu yefilimu ethengisiweyo ukuza kuthi ga ngoku ilandelayo. I-FDA ivumile ukwenziwa kweefilimu ezingama-82 zefilimu (kubandakanya abavelisi abahlukeneyo), kunye neenkcazo ze-PMDA ezivunywayo ezili-17 (kubandakanywa abavelisi abakhoyo, kodwa kuthelekiswa neendlela zokwenza iifilimu ziya kudlala indima ebalulekileyo kuphuhliso olulandelayo kuphuhliso olulandelayo.
Ngo-2004, intengiso yehlabathi yetekhnoloji yefilimu ye-OTC kunye neMveliso yeMveliso ye-US i-US $ 25 ye-US $ 500 yezigidi ngo-2000 yezigidigidi ngo-2015.
Ubume bangoku bokuphuhliswa kwekhaya kunye nokusetyenziswa kwamalungiselelo efilimu yomlomo
Akukho mfuneko yefilimu yomlomo ivunyiwe kwintengiso eTshayina, kwaye zonke zikwimeko yophando. Abavelisi kunye neentlobo ezahlukeneyo ezivunyiweyo kwizicelo zeklinikhi kunye nobhaliso kwindawo yovavanyo zezi zilandelayo:
Abavelisi basekhaya ababhengeza inani elikhulu leearhente zokuchithwa komlomo yi-QLue (ii-7 ezahlukeneyo), i-hengrui (iintlobo-4), i-Shangrui (iindidi zeSichuan bailical (iipesenti ezi-4).
Esona sicelo sisekhaya somlomo yi-Arhente yokuGcina i-Ondonsensols ye-Ondensel
Okwangoku, isabelo sentengiso se-membrane yomlomo (ngaphandle kwemveliso yokuphefumla) igxile ikakhulu kwimarike yaseNtshona Melika. Ngobunzulu kunye nophuhliso lweephanda ezahlukeneyo kwi-membrane kwangoko, kunye nokukhuthaza ezo mveliso eYurophu naseAsia, ndiyakholelwa ukuba le fomu ye-dosage inamandla okuthengisa amayeza, kwiimveliso zezempilo kunye neemveliso zezempilo kunye neemveliso zezempilo kunye neemveliso zezempilo.
Ixesha leposi: May-28-2022
